Lifespan: Why We Age―and Why We Don't Have To - cover

Lifespan

Why We Age―and Why We Don’t Have To

By David A. Sinclair, Matthew D. LaPlante

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About the book

David A. Sinclair and Matthew D. LaPlante argue that aging is a disease, and that it can be treated. Sinclair, a Harvard Medical School scientist, presents a theory in which an ancient genetic survival circuit both drives aging and offers a way to reverse it, and describes how activating vitality genes could slow the process. The authors survey the hallmarks of aging, among them DNA damage that destabilizes the genome, changes to the epigenome, exhausted stem cells and inflammation. Research from Sinclair's own lab sits alongside lifestyle changes such as cold exposure, intermittent fasting and exercise at the right intensity. Its three parts deal with the past, present and future of the field.

Andrew Huberman called it a terrific book on aging as a disease and on longevity treatments now and to come. Bulletproof founder Dave Asprey endorsed it, describing Sinclair as a rock star of aging research.

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This book has 3 recommendations

Dave Asprey (Founder and CEO/Bulletproof)

Prepare to have your mind blown. You are holding in your hands the precious results of decades of work, as shared by Dr. David Sinclair, the rock star of aging and human longevity.

Jason Fung (MD, Author)

Imagine a world in which we can live long enough to meet not just our grandchildren, but our great-grandchildren. This is Sinclair’s vision for the future of humankind, a vision that looks to science, nature, history, and even politics to make the case that it is possible to live well into our hundreds. Lifespan is boldly leading the way

Andrew Huberman

"Lifespan" is this terrific book about aging as a disease and the future and present of longevity treatments.

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David A. Sinclair, Matthew D. LaPlante